For years, I’ve struggled with acne-prone skin, and while I’ve finally gotten it under control, I’m now noticing another challenge creeping in—fine lines and wrinkles. At 36, this was the wake-up call I needed to start focusing on anti-aging skincare, something I’d somewhat neglected while battling acne. So, when Depology reached out to me to try their Peptide Complex Serum and Matrixyl® 3000 Serum—both designed to target wrinkles and boost collagen—I was excited to give them a go. Here’s what I found…

About Depology

Depology is a Korean skincare brand specializing in anti-aging products backed by scientific research and rigorous testing. They blend traditional ingredients with trending innovations to create effective skincare essentials that fit seamlessly into any routine.

The brand has recently gained popularity on TikTok, with beauty influencers raving about their serums. With over 2,000 glowing reviews, I couldn’t wait to try them myself.

“From our launch with microneedle eye patches to our current range, Dēpology stays true to our philosophy of powerful, preventative formulas using a gentle, noninvasive approach.”

Depology

Peptide Complex 10%

The Peptide Complex 10% Serum contains Argireline™, a multi-peptide formula designed to prevent wrinkles caused by muscle movement and stimulate collagen production. It also hydrates the skin, leaving it feeling refreshed.

As a newcomer to serums, I appreciated the clear instructions on the packaging. After cleansing and toning, I applied a few drops morning and night, focusing on problem areas like my neck and crow’s feet. The serum absorbed quickly, making it easy to layer with the rest of my routine.

Matrixyl® 3000

The Matrixyl® 3000 Collagen Boosting Serum is one of Depology’s star products. It hydrates skin and reduces signs of aging by encouraging collagen production. Used alongside the Peptide Complex serum, these two products complement each other perfectly—while Argireline™ relaxes facial muscles to reduce wrinkles, Matrixyl® boosts collagen for firmer skin.

Depology also offers Micro-Dart Patches that can be used with Matrixyl® 3000 for enhanced results. I haven’t tried these yet, but they’re definitely on my shopping list after reading great reviews.

Depology

My Honest Experience

After using both serums for a few weeks, I’m impressed. It’s still early days, but I’ve already noticed my fine lines and wrinkles looking softer. Importantly, with my sensitive, acne-prone skin, I was worried about breakouts, but these products have been gentle and have left my skin feeling smooth and hydrated.

If you’re searching for effective wrinkle defense products, I’d recommend giving these serums a try. And if you want expert opinions, check out what dermatologists say about Depology’s formulas [here].